National Academies of Sciences%2c Engineering%2c and Medicine: Re-Thinking the Acceptable Macronutrient Distribution Range for the 21st Century: A Letter Report Acceptable Macronutrient Distribution Ranges (AMDRs) for carbohydrate, fat, and protein were developed and incorporated into the Dietary Reference Intakes (DRI) framework to address the growing body ... Re-Thinking the Acceptable Macronutrient Distribution Range for the 21st Century: A Letter Report