Skin manifestations are common in small- and medium-vessel autoimmune vasculitis, and clinical risk factors might help in sorting out who has severe systemic disease for some subtypes, studies showed. Medscape: Severe Skin Manifestations in Pediatric IgA Vasculitis a Warning Sign of Higher Relapse Risk Children with IgA vasculitis who present with severe persistent skin manifestations, such as hemorrhagic vesicles, ulceration, or necrosis, are at higher risk for relapse and should be followed for a ... Severe Skin Manifestations in Pediatric IgA Vasculitis a Warning Sign of Higher Relapse Risk People who have conditions in which their immune systems attack their own bodies by mistake may be at higher risk of vasculitis.

Understanding the Context

These conditions include lupus, rheumatoid arthritis and scleroderma. Vasculitis is an autoimmune disease that causes inflammation in your blood vessels. The swelling makes it hard for blood to flow through your affected vessels, which can cause organ and tissue damage. Vasculitis is primarily caused by leukocyte migration and resultant damage.

Key Insights

Although both occur in vasculitides, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities. Vasculitis is a general term for inflammation in your blood vessels. Learn more about the causes, complications, symptoms, types, diagnosis, treatment, and prognosis of vasculitis.