A national cohort study compares the safety and efficacy of weight-based and fixed-dose pembrolizumab regimens in patients with advanced non-small cell lung cancer. Yahoo Finance: European Commission Approves KEYTRUDA® (pembrolizumab) Plus Paclitaxel ± Bevacizumab for the Treatment of Adults With PD-L1 (CPS ≥1) Platinum-Resistant Recurrent Ovarian ... Merck (NYSE: MRK), known as MSD outside of the United States and Canada, announced that KEYTRUDA® (pembrolizumab), in combination with paclitaxel, with or without bevacizumab, is approved in the ...

Understanding the Context

European Commission Approves KEYTRUDA® (pembrolizumab) Plus Paclitaxel ± Bevacizumab for the Treatment of Adults With PD-L1 (CPS ≥1) Platinum-Resistant Recurrent Ovarian ... A study published April 10 in The Lancet reports that the anti-PD-1 immunotherapy pembrolizumab (brand name Keytruda) significantly improved overall survival in adults with platinum-resistant ovarian ... ascopubs.org: Long-term results of the randomized, phase 3 KEYNOTE-412 trial of pembrolizumab (pembro) or placebo (pbo) plus concurrent chemoradiotherapy (CRT) for unresected, locally ... Neoadjuvant and adjuvant pembrolizumab plus standard of care (SOC) in resectable locally advanced head and neck squamous cell carcinoma (LA HNSCC): Exploratory efficacy analyses of the phase 3 KEYNOTE ...

Key Insights

Long-term results of the randomized, phase 3 KEYNOTE-412 trial of pembrolizumab (pembro) or placebo (pbo) plus concurrent chemoradiotherapy (CRT) for unresected, locally ... Please provide your email address to receive an email when new articles are posted on . The addition of pembrolizumab improved pathologic complete response rate. The pembrolizumab regimen did not ... Healio: Pembrolizumab plus olaparib does not extend survival in triple-negative breast cancer Please provide your email address to receive an email when new articles are posted on .

Final Thoughts

Researchers observed no significant PFS or OS benefit with pembrolizumab-olaparib vs. pembrolizumab-chemotherapy ... Renal & Urology News: Adding Pembrolizumab to Docetaxel Not Beneficial in Previously Treated mCRPC Pembrolizumab plus docetaxel does not improve radiographic progression-free survival or overall survival compared with docetaxel alone. Adding pembrolizumab to docetaxel is not better than docetaxel ... The pembrolizumab regimen reduced the risk of disease progression or death by 28% and reduced the risk of death by 24% compared with placebo plus paclitaxel with or without bevacizumab. The Food and ...