People with Sweet's syndrome often wake up with a fever, body aches, and blisters on their neck, limbs and face. Also known as acute febrile neutrophilic dermatosis, it is an inflammatory skin disease ... Shared inflammatory signatures in vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome, myelodysplasia cutis (MDS-cutis), and Sweet syndrome (SS) suggest interferon pathways as ...

Understanding the Context

Please provide your email address to receive an email when new articles are posted on . VEXAS syndrome often has skin manifestations, but these often mimic symptoms of Sweet syndrome or vasculitis. Acute febrile neutrophilic dermatosis is a rare skin condition characterised by a sudden onset of painful, inflamed skin lesions associated with fever. Acute febrile neutrophilic dermatosis also has the eponymous name, Sweet syndrome, named after Dr Robert Douglas Sweet from Plymouth, England, who first described it in 1964.

Key Insights

Neutrophilic dermatosis of the hands is considered a localised variant of acute febrile neutrophilic dermatosis or Sweet syndrome, in which bluish or grey abscess -like nodules and blisters arise on the hands. They most often occur on the back of the hands, thumb or fingers but sometimes arise on the palmar surface. These nodules may ulcerate. View pictures of acute febrile neutrophilic dermatosis (Sweet syndrome) in the gallery below. Acute febrile neutrophilic dermatosis is an uncommon skin condition characterised by fever and inflamed or blistered skin and mucosal lesions.

Final Thoughts

Neutrophilic dermatoses are autoinflammatory conditions often associated with systemic disease. This rare skin condition can cause painful skin bumps or lesions. While there’s a lot that’s still unknown about what causes Sweet syndrome, many factors may play a role in its development. Sweet ... Sweet's syndrome is an uncommon skin disorder of unkown aetiology characterised by painful erythematous plaques, and associated with pyrexia, marked leucocytosis and elevated erythrocyte sedimentation ... Sweet syndrome is a rare inflammatory condition.

It involves a sudden onset of fever and painful skin rashes. Sweet syndrome, or acute febrile neutrophilic dermatosis, is a rare skin condition. It ...