In clinical trials, up to 22% of people on Mounjaro – just over 1 in 5 – had nausea. Up to 1 in 10 people reported vomiting, too. Larger doses are more likely to cause these side effects.

Understanding the Context

Mounjaro is used to help lower blood sugar levels in diabetics, and manage weight. However, there are some Mounjaro side effects like nausea and diarrhea. Learn about Mounjaro's more common, mild, and serious side effects and how to manage them. Tirzepatide (Mounjaro, Zepbound) can cause nausea, vomiting, and burping.

Key Insights

Here are the tirzepatide side effects you want to know about before taking it. Common side effects of Mounjaro (tirzepatide) include nausea, vomiting, and fatigue. In some severe cases, Mounjaro may also cause stomach paralysis. The most common Mounjaro side effects include nausea, diarrhea, vomiting, constipation, decreased appetite, indigestion and abdominal pain. Less than 5% of patients report experiencing these side effects according to manufacturer Eli Lilly.

Final Thoughts

The most common Mounjaro side effects to be aware of are diarrhea, vomiting, constipation, nausea (mild to moderate), decreased appetite, and abdominal pain. For most people, stomach side effects lessen or go away after a few weeks of treatment. Low blood sugar may also be common. Our Mounjaro (tirzepatide) Injection, for Subcutaneous Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.