Nature: Effect of prednisone plus either adalimumab or cyclosporine on dermatological symptoms in Vogt-Koyanagi-Harada disease: systemic outcomes from a randomized trial Effect of prednisone plus either adalimumab or cyclosporine on dermatological symptoms in Vogt-Koyanagi-Harada disease: systemic outcomes from a randomized trial Vogt-Koyanagi-Harada (VKH) disease is defined as a bilateral granulomatous panuveitis, with or without extraocular manifestations, affecting young adults. Vogt in 1906 and Koyanagi in 1929 described the same disorder independently. Vogt-Koyanagi-Harada disease (VKH disease) affects the eyes, ears, nervous system, and skin.

Understanding the Context

The symptoms of VKH occur in different phases. The early symptoms include headaches, eye pain, and dizziness. These are followed by hearing loss and inflammation of the eye (panuveitis). Vogt-Koyanagi-Harada disease causes inflammation inside your eyes.

Key Insights

Later phases can damage your hearing and cause skin and hair changes. Treatment can prevent permanent complications. Vogt–Koyanagi–Harada disease (VKH) is a multisystem disease of presumed autoimmune cause that affects melanin -pigmented tissues. Vogt-Koyanagi-Harada syndrome (VKH) is a multisystem disease that presents with a combination of ophthalmological, neurological, and dermatological signs and symptoms. Vogt-Koyanagi-Harada (VKH) disease is a multisystemic disorder characterized by granulomatous panuveitis with exudative retinal detachments that is often associated with neurologic and...

Final Thoughts

Vogt-Koyanagi-Harada (VKH) disease is an idiopathic immune-related sickness that affects multiple systems and melanocytes in organs such as the uvea, ear, and meninges. Learn about Vogt-Koyanagi-Harada Disease, including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find.