In a study, veterans who used TNF blockers to treat inflammatory bowel disease had an increased risk for kidney function decline. Anti-tumor necrosis factor (anti-TNF) therapy may increase the risk ... EurekAlert!: Tumor Necrosis Factor Superfamily Member 15 (TNFSF15) rs4979462 Variant and TNFSF15 serum levels evaluation in systemic lupus erythematosus Tumor necrosis factor (TNF) superfamily member 15 (TNFSF15) may have the potential to control vascular homeostasis and inflammation.

Understanding the Context

Through binding to death receptor 3 (TNFRSF25), TNFSF15 promotes ... Tumor Necrosis Factor Superfamily Member 15 (TNFSF15) rs4979462 Variant and TNFSF15 serum levels evaluation in systemic lupus erythematosus Worries that tumor necrosis factor (TNF) inhibitors may exacerbate or even cause lung disease in patients with rheumatoid arthritis (RA) are unfounded, at least for U.S. military veterans, a new study ... Tumor necrosis factor (TNF) inhibitors protect patients with axial spondyloarthritis (axSpA) from hip and spine fractures better than other drugs.

Key Insights

Large US insurance claims database study comparing ... Renal & Urology News: Anti-Tumor Necrosis Factor Therapy for IBD Tied to Kidney Function Decline Early treatment of pediatric Crohn’s disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas, a particularly debilitating complication of Crohn’s ...