Please provide your email address to receive an email when new articles are posted on . Providers should educate patients when prescribing glucocorticoid therapy. Tapering off glucocorticoids should ...

Understanding the Context

Based on the European Society of Endocrinology/Endocrine Society joint clinical guideline, which of the statements about glucocorticoid tapering are correct? A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the ... Medscape: T-Cell Glucocorticoid Receptor is Required to Suppress COX-2-Mediated Lethal Immune Activation Glucocorticoid-induced osteoporosis is a common condition that results in significant morbidity and mortality. The skeletal effects of glucocorticoids include both direct and indirect actions on bone ...

Key Insights

The New England Journal of Medicine: Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. We performed a randomized, double-placebo, double-blind clinical ... ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ... Glucocorticoids are steroid hormones that help regulate the immune system. They also play a key role in the metabolism of fats, proteins, and glucose.

Final Thoughts

Glucocorticoids come in natural and synthetic ... Treatment for rheumatoid arthritis (RA) is generally therapy with disease-modifying anti-rheumatic drugs (DMARDs). However, glucocorticoids are also used in the short term, particularly when just ... The American Journal of Managed Care: Glucocorticoids Reduce Comorbidity Frequency in Adults With DMD, Study Finds A retrospective analysis found glucocorticoid treatment to reduce comorbidities in adults with Duchenne muscular dystrophy (DMD) and assessed the relationship between anthropometric measures and ... Glucocorticoids are a type of corticosteroid hormone that is very effective at reducing inflammation and suppressing the immune system. Inflammation is the way our immune system responds to harmful substances and trauma and is part of our healing process.

Glucocorticoids are part of the feedback mechanism in the immune system, which reduces certain aspects of immune function, such as inflammation. They are therefore used in medicine to treat diseases caused by an overactive immune system, such as allergies, asthma, autoimmune diseases, and sepsis. Scientifically, glucocorticoids are a specific subgroup of corticosteroids. But they’re commonly used as interchangeable names for the same kinds of drugs.