Healthline: What to Know About Bull’s-Eye or Target Lesions with Erythema Migrans and Erythema Multiforme Erythema migrans and erythema multiforme both cause target- or bull’s-eye-shaped lesions. Erythema migrans is due to Lyme disease. Erythema multiforme is an immune-mediated hypersensitivity skin ...

Understanding the Context

What to Know About Bull’s-Eye or Target Lesions with Erythema Migrans and Erythema Multiforme Erythema migrans is the most common manifestation of Lyme disease. Recurrences are not uncommon, and although they are usually attributed to reinfection rather than relapse of the original infection, ... National Institute for Health and Care Excellence: Quality statement 1: Erythema migrans People presenting with erythema migrans are diagnosed and treated for Lyme disease based on clinical assessment, without laboratory testing. Proportion of people diagnosed with Lyme disease based on ...

Key Insights

People with suspected Lyme disease without erythema migrans who have a negative enzyme-linked immunosorbent assay (ELISA) test carried out within 4 weeks of their symptoms starting have the test ... Erythema migrans (EM) is classically described as a flat, blanchable, annular, erythematous skin lesion with or without central clearing, occurring at the site of Borrelia burgdorferi inoculation. The ...